LymphedemaV1, Main, Exploration, bibRecord, 002E61

A Longitudinal Analysis of the Effect of Mass Drug Administration on Acute Inflammatory Episodes and Disease Progression in Lymphedema Patients in Léogane, Haiti

Identifieur interne : 002E61 ( Main/Exploration ); précédent : 002E60; suivant : 002E62

A Longitudinal Analysis of the Effect of Mass Drug Administration on Acute Inflammatory Episodes and Disease Progression in Lymphedema Patients in Léogane, Haiti

Auteurs : Brittany A. Eddy ; Anna J. Blackstock ; John M. Williamson ; David G. Addiss ; Thomas G. Streit ; Valery M. Beau De Rochars ; Leanne M. Fox

Source :

The American Journal of Tropical Medicine and Hygiene [ 0002-9637 ] ; 2014.

RBID : PMC:3886433

Descripteurs français

KwdFr :
- Adolescent, Adulte, Adulte d'âge moyen, Albendazole (administration et posologie), Albendazole (usage thérapeutique), Antihelminthiques (administration et posologie), Antihelminthiques (usage thérapeutique), Diéthylcarbamazine (administration et posologie), Diéthylcarbamazine (usage thérapeutique), Enfant, Femelle, Filariose lymphatique (anatomopathologie), Filariose lymphatique (traitement médicamenteux), Filariose lymphatique (épidémiologie), Haïti (épidémiologie), Humains, Inflammation (anatomopathologie), Ivermectine (administration et posologie), Ivermectine (usage thérapeutique), Jeune adulte, Mâle, Sujet âgé.
MESH :
- administration et posologie : Albendazole, Antihelminthiques, Diéthylcarbamazine, Ivermectine.
- anatomopathologie : Filariose lymphatique, Inflammation.
- traitement médicamenteux : Filariose lymphatique.
- usage thérapeutique : Albendazole, Antihelminthiques, Diéthylcarbamazine, Ivermectine.
- épidémiologie : Filariose lymphatique, Haïti.
- Adolescent, Adulte, Adulte d'âge moyen, Enfant, Femelle, Humains, Jeune adulte, Mâle, Sujet âgé.
Wicri :
- geographic : Haïti.

English descriptors

KwdEn :
- Adolescent, Adult, Aged, Albendazole (administration & dosage), Albendazole (therapeutic use), Anthelmintics (administration & dosage), Anthelmintics (therapeutic use), Child, Diethylcarbamazine (administration & dosage), Diethylcarbamazine (therapeutic use), Elephantiasis, Filarial (drug therapy), Elephantiasis, Filarial (epidemiology), Elephantiasis, Filarial (pathology), Female, Haiti (epidemiology), Humans, Inflammation (pathology), Ivermectin (administration & dosage), Ivermectin (therapeutic use), Male, Middle Aged, Young Adult.
MESH :
- chemical , administration & dosage : Albendazole, Anthelmintics, Diethylcarbamazine, Ivermectin.
- chemical , therapeutic use : Albendazole, Anthelmintics, Diethylcarbamazine, Ivermectin.
- geographic , epidemiology : Haiti.
- drug therapy : Elephantiasis, Filarial.
- epidemiology : Elephantiasis, Filarial.
- pathology : Elephantiasis, Filarial, Inflammation.
- Adolescent, Adult, Aged, Child, Female, Humans, Male, Middle Aged, Young Adult.

Abstract

We conducted a longitudinal analysis of 117 lymphedema patients in a filariasis-endemic area of Haiti during 1995–2008. No difference in lymphedema progression between those who received or did not receive mass drug administration (MDA) was found on measures of foot (P = 0.24), ankle (P = 0.87), or leg (P = 0.46) circumference; leg volume displacement (P = 0.09), lymphedema stage (P = 0.93), or frequency of adenolymphangitis (ADL) episodes (P = 0.57). Rates of ADL per year were greater after initiation of MDA among both groups (P < 0.01). Nevertheless, patients who received MDA reported improvement in four areas of lymphedema-related quality of life (P ≤ 0.01). Decreases in foot and ankle circumference and ADL episodes were observed during the 1995-1998 lymphedema management study (P ≤ 0.01). This study represents the first longitudinal, quantitative, leg-specific analysis examining the clinical effect of diethylcarbamazine on lymphedema progression and ADL episodes.

Url:

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3886433

DOI: 10.4269/ajtmh.13-0317
PubMed: 24218408
PubMed Central: 3886433

Affiliations:

Le document en format XML

<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">A Longitudinal Analysis of the Effect of Mass Drug Administration on Acute Inflammatory Episodes and Disease Progression in Lymphedema Patients in Léogane, Haiti</title>
<author><name sortKey="Eddy, Brittany A" sort="Eddy, Brittany A" uniqKey="Eddy B" first="Brittany A." last="Eddy">Brittany A. Eddy</name>
</author>
<author><name sortKey="Blackstock, Anna J" sort="Blackstock, Anna J" uniqKey="Blackstock A" first="Anna J." last="Blackstock">Anna J. Blackstock</name>
</author>
<author><name sortKey="Williamson, John M" sort="Williamson, John M" uniqKey="Williamson J" first="John M." last="Williamson">John M. Williamson</name>
</author>
<author><name sortKey="Addiss, David G" sort="Addiss, David G" uniqKey="Addiss D" first="David G." last="Addiss">David G. Addiss</name>
</author>
<author><name sortKey="Streit, Thomas G" sort="Streit, Thomas G" uniqKey="Streit T" first="Thomas G." last="Streit">Thomas G. Streit</name>
</author>
<author><name sortKey="Beau De Rochars, Valery M" sort="Beau De Rochars, Valery M" uniqKey="Beau De Rochars V" first="Valery M." last="Beau De Rochars">Valery M. Beau De Rochars</name>
</author>
<author><name sortKey="Fox, Leanne M" sort="Fox, Leanne M" uniqKey="Fox L" first="Leanne M." last="Fox">Leanne M. Fox</name>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">PMC</idno>
<idno type="pmid">24218408</idno>
<idno type="pmc">3886433</idno>
<idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3886433</idno>
<idno type="RBID">PMC:3886433</idno>
<idno type="doi">10.4269/ajtmh.13-0317</idno>
<date when="2014">2014</date>
<idno type="wicri:Area/Pmc/Corpus">002C06</idno>
<idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">002C06</idno>
<idno type="wicri:Area/Pmc/Curation">002C05</idno>
<idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Curation">002C05</idno>
<idno type="wicri:Area/Pmc/Checkpoint">001E29</idno>
<idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Checkpoint">001E29</idno>
<idno type="wicri:source">PubMed</idno>
<idno type="wicri:Area/PubMed/Corpus">001841</idno>
<idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">001841</idno>
<idno type="wicri:Area/PubMed/Curation">001841</idno>
<idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">001841</idno>
<idno type="wicri:Area/PubMed/Checkpoint">001841</idno>
<idno type="wicri:explorRef" wicri:stream="Checkpoint" wicri:step="PubMed">001841</idno>
<idno type="wicri:Area/Ncbi/Merge">005F23</idno>
<idno type="wicri:Area/Ncbi/Curation">005F23</idno>
<idno type="wicri:Area/Ncbi/Checkpoint">005F23</idno>
<idno type="wicri:doubleKey">0002-9637:2014:Eddy B:a:longitudinal:analysis</idno>
<idno type="wicri:Area/Main/Merge">002E66</idno>
<idno type="wicri:Area/Main/Curation">002E61</idno>
<idno type="wicri:Area/Main/Exploration">002E61</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">A Longitudinal Analysis of the Effect of Mass Drug Administration on Acute Inflammatory Episodes and Disease Progression in Lymphedema Patients in Léogane, Haiti</title>
<author><name sortKey="Eddy, Brittany A" sort="Eddy, Brittany A" uniqKey="Eddy B" first="Brittany A." last="Eddy">Brittany A. Eddy</name>
</author>
<author><name sortKey="Blackstock, Anna J" sort="Blackstock, Anna J" uniqKey="Blackstock A" first="Anna J." last="Blackstock">Anna J. Blackstock</name>
</author>
<author><name sortKey="Williamson, John M" sort="Williamson, John M" uniqKey="Williamson J" first="John M." last="Williamson">John M. Williamson</name>
</author>
<author><name sortKey="Addiss, David G" sort="Addiss, David G" uniqKey="Addiss D" first="David G." last="Addiss">David G. Addiss</name>
</author>
<author><name sortKey="Streit, Thomas G" sort="Streit, Thomas G" uniqKey="Streit T" first="Thomas G." last="Streit">Thomas G. Streit</name>
</author>
<author><name sortKey="Beau De Rochars, Valery M" sort="Beau De Rochars, Valery M" uniqKey="Beau De Rochars V" first="Valery M." last="Beau De Rochars">Valery M. Beau De Rochars</name>
</author>
<author><name sortKey="Fox, Leanne M" sort="Fox, Leanne M" uniqKey="Fox L" first="Leanne M." last="Fox">Leanne M. Fox</name>
</author>
</analytic>
<series><title level="j">The American Journal of Tropical Medicine and Hygiene</title>
<idno type="ISSN">0002-9637</idno>
<idno type="eISSN">1476-1645</idno>
<imprint><date when="2014">2014</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
</fileDesc>
<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adolescent</term>
<term>Adult</term>
<term>Aged</term>
<term>Albendazole (administration & dosage)</term>
<term>Albendazole (therapeutic use)</term>
<term>Anthelmintics (administration & dosage)</term>
<term>Anthelmintics (therapeutic use)</term>
<term>Child</term>
<term>Diethylcarbamazine (administration & dosage)</term>
<term>Diethylcarbamazine (therapeutic use)</term>
<term>Elephantiasis, Filarial (drug therapy)</term>
<term>Elephantiasis, Filarial (epidemiology)</term>
<term>Elephantiasis, Filarial (pathology)</term>
<term>Female</term>
<term>Haiti (epidemiology)</term>
<term>Humans</term>
<term>Inflammation (pathology)</term>
<term>Ivermectin (administration & dosage)</term>
<term>Ivermectin (therapeutic use)</term>
<term>Male</term>
<term>Middle Aged</term>
<term>Young Adult</term>
</keywords>
<keywords scheme="KwdFr" xml:lang="fr"><term>Adolescent</term>
<term>Adulte</term>
<term>Adulte d'âge moyen</term>
<term>Albendazole (administration et posologie)</term>
<term>Albendazole (usage thérapeutique)</term>
<term>Antihelminthiques (administration et posologie)</term>
<term>Antihelminthiques (usage thérapeutique)</term>
<term>Diéthylcarbamazine (administration et posologie)</term>
<term>Diéthylcarbamazine (usage thérapeutique)</term>
<term>Enfant</term>
<term>Femelle</term>
<term>Filariose lymphatique (anatomopathologie)</term>
<term>Filariose lymphatique (traitement médicamenteux)</term>
<term>Filariose lymphatique (épidémiologie)</term>
<term>Haïti (épidémiologie)</term>
<term>Humains</term>
<term>Inflammation (anatomopathologie)</term>
<term>Ivermectine (administration et posologie)</term>
<term>Ivermectine (usage thérapeutique)</term>
<term>Jeune adulte</term>
<term>Mâle</term>
<term>Sujet âgé</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="administration & dosage" xml:lang="en"><term>Albendazole</term>
<term>Anthelmintics</term>
<term>Diethylcarbamazine</term>
<term>Ivermectin</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="therapeutic use" xml:lang="en"><term>Albendazole</term>
<term>Anthelmintics</term>
<term>Diethylcarbamazine</term>
<term>Ivermectin</term>
</keywords>
<keywords scheme="MESH" type="geographic" qualifier="epidemiology" xml:lang="en"><term>Haiti</term>
</keywords>
<keywords scheme="MESH" qualifier="administration et posologie" xml:lang="fr"><term>Albendazole</term>
<term>Antihelminthiques</term>
<term>Diéthylcarbamazine</term>
<term>Ivermectine</term>
</keywords>
<keywords scheme="MESH" qualifier="anatomopathologie" xml:lang="fr"><term>Filariose lymphatique</term>
<term>Inflammation</term>
</keywords>
<keywords scheme="MESH" qualifier="drug therapy" xml:lang="en"><term>Elephantiasis, Filarial</term>
</keywords>
<keywords scheme="MESH" qualifier="epidemiology" xml:lang="en"><term>Elephantiasis, Filarial</term>
</keywords>
<keywords scheme="MESH" qualifier="pathology" xml:lang="en"><term>Elephantiasis, Filarial</term>
<term>Inflammation</term>
</keywords>
<keywords scheme="MESH" qualifier="traitement médicamenteux" xml:lang="fr"><term>Filariose lymphatique</term>
</keywords>
<keywords scheme="MESH" qualifier="usage thérapeutique" xml:lang="fr"><term>Albendazole</term>
<term>Antihelminthiques</term>
<term>Diéthylcarbamazine</term>
<term>Ivermectine</term>
</keywords>
<keywords scheme="MESH" qualifier="épidémiologie" xml:lang="fr"><term>Filariose lymphatique</term>
<term>Haïti</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Adolescent</term>
<term>Adult</term>
<term>Aged</term>
<term>Child</term>
<term>Female</term>
<term>Humans</term>
<term>Male</term>
<term>Middle Aged</term>
<term>Young Adult</term>
</keywords>
<keywords scheme="MESH" xml:lang="fr"><term>Adolescent</term>
<term>Adulte</term>
<term>Adulte d'âge moyen</term>
<term>Enfant</term>
<term>Femelle</term>
<term>Humains</term>
<term>Jeune adulte</term>
<term>Mâle</term>
<term>Sujet âgé</term>
</keywords>
<keywords scheme="Wicri" type="geographic" xml:lang="fr"><term>Haïti</term>
</keywords>
</textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en"><p>We conducted a longitudinal analysis of 117 lymphedema patients in a filariasis-endemic area of Haiti during 1995–2008. No difference in lymphedema progression between those who received or did not receive mass drug administration (MDA) was found on measures of foot (<italic>P</italic>
 = 0.24), ankle (<italic>P</italic>
 = 0.87), or leg (<italic>P</italic>
 = 0.46) circumference; leg volume displacement (<italic>P</italic>
 = 0.09), lymphedema stage (<italic>P</italic>
 = 0.93), or frequency of adenolymphangitis (ADL) episodes (<italic>P</italic>
 = 0.57). Rates of ADL per year were greater after initiation of MDA among both groups (<italic>P</italic>
 < 0.01). Nevertheless, patients who received MDA reported improvement in four areas of lymphedema-related quality of life (<italic>P</italic>
 ≤ 0.01). Decreases in foot and ankle circumference and ADL episodes were observed during the 1995-1998 lymphedema management study (<italic>P</italic>
 ≤ 0.01). This study represents the first longitudinal, quantitative, leg-specific analysis examining the clinical effect of diethylcarbamazine on lymphedema progression and ADL episodes.</p>
</div>
</front>
</TEI>
<affiliations><list></list>
<tree><noCountry><name sortKey="Addiss, David G" sort="Addiss, David G" uniqKey="Addiss D" first="David G." last="Addiss">David G. Addiss</name>
<name sortKey="Beau De Rochars, Valery M" sort="Beau De Rochars, Valery M" uniqKey="Beau De Rochars V" first="Valery M." last="Beau De Rochars">Valery M. Beau De Rochars</name>
<name sortKey="Blackstock, Anna J" sort="Blackstock, Anna J" uniqKey="Blackstock A" first="Anna J." last="Blackstock">Anna J. Blackstock</name>
<name sortKey="Eddy, Brittany A" sort="Eddy, Brittany A" uniqKey="Eddy B" first="Brittany A." last="Eddy">Brittany A. Eddy</name>
<name sortKey="Fox, Leanne M" sort="Fox, Leanne M" uniqKey="Fox L" first="Leanne M." last="Fox">Leanne M. Fox</name>
<name sortKey="Streit, Thomas G" sort="Streit, Thomas G" uniqKey="Streit T" first="Thomas G." last="Streit">Thomas G. Streit</name>
<name sortKey="Williamson, John M" sort="Williamson, John M" uniqKey="Williamson J" first="John M." last="Williamson">John M. Williamson</name>
</noCountry>
</tree>
</affiliations>
</record>

Pour manipuler ce document sous Unix (Dilib)

EXPLOR_STEP=$WICRI_ROOT/Wicri/Sante/explor/LymphedemaV1/Data/Main/Exploration

HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 002E61 | SxmlIndent | more

HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 002E61 | SxmlIndent | more

Pour mettre un lien sur cette page dans le réseau Wicri

{{Explor lien
   |wiki=    Wicri/Sante
   |area=    LymphedemaV1
   |flux=    Main
   |étape=   Exploration
   |type=    RBID
   |clé=     PMC:3886433
   |texte=   A Longitudinal Analysis of the Effect of Mass Drug Administration on Acute Inflammatory Episodes and Disease Progression in Lymphedema Patients in Léogane, Haiti
}}

Pour générer des pages wiki

HfdIndexSelect -h $EXPLOR_AREA/Data/Main/Exploration/RBID.i   -Sk "pubmed:24218408" \
       | HfdSelect -Kh $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd   \
       | NlmPubMed2Wicri -a LymphedemaV1

This area was generated with Dilib version V0.6.31.
Data generation: Sat Nov 4 17:40:35 2017. Site generation: Tue Feb 13 16:42:16 2024

Serveur d'exploration sur le lymphœdème

A Longitudinal Analysis of the Effect of Mass Drug Administration on Acute Inflammatory Episodes and Disease Progression in Lymphedema Patients in Léogane, Haiti

A Longitudinal Analysis of the Effect of Mass Drug Administration on Acute Inflammatory Episodes and Disease Progression in Lymphedema Patients in Léogane, Haiti

Source :

Descripteurs français

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri

Pour générer des pages wiki

	Serveur d'exploration sur le lymphœdème
	Attention, ce site est en cours de développement ! Attention, site généré par des moyens informatiques à partir de corpus bruts. Les informations ne sont donc pas validées.